In the main event on ESPN+, former heavyweight champion Junior dos Santos finished Derrick Lewis in the second round.
The card marked the debut for the UFC in Wichita, Kansas.
For dos Santos, the win was his 10th finish in the UFC, tying him with fellow former titleholder Cain Velasquez and Lewis all-time in the division. He has scored 15 career wins via knockout or TKO.
Elizeu Zaleski dos Santos locked in a rear-naked choke on Curtis Millender, earning a first round submission and his seventh consecutive win.
Niko Price, Blagoy Ivanov, Beneil Dariush and Omari Akhmedov also scored main card victories on the night.
On the prelims, Grant Dawson took advantage of his opportunity, besting Julian Erosa via decision. Dawson earned scores of 30-26, 30-27 and 29-27.
Complete results are below:
Junior dos Santos def. Derrick Lewis via TKO (strikes) at 1:58 of Round 2
Elizeu Zaleski dos Santos def. Curtis Millender via submission (rear-naked choke) at 2:35 of Round 1
Niko Price def. Tim Means via KO (strike) at 4:50 of Round 1
Blagoy Ivanov def. Ben Rothwell via unanimous decision (29-28, 29-28, 29-28)
Beneil Dariush def. Drew Dober via submission (triangle armbar) at 4:41 of Round 2
Omari Akhmedov def. Tim Boetsch via unanimous decision (30-27, 30-27, 30-27)
Anthony Rocco Martin def. Sergio Moraes via unanimous decision (30-27, 30-27, 30-27)
Yana Kunitskaya def. Marion Reneau via unanimous decision (29-28, 29-28, 29-28)
Grant Dawson def. Julian Erosa via unanimous decision (30-26, 30-27, 29-27)
Maurice Greene def. Jeff Hughes via split decision (29-28, 28-29, 29-28)
Matt Schnell def. Louis Smolka via submission (triangle choke) at 3:18 of Round 1
Alex Morono def. Zak Ottow via verbal submission (elbows) at 3:34 of Round 1
Alex White def. Dan Moret via unanimous decision (29-28, 29-28, 29-28)